This guide is a valuable resource designed to support psychosocial professionals assisting vulnerable migrant populations in Morocco. It addresses the need to better understand mental health challenges linked to the structural difficulties faced by these communities and outlines pathways to provide appropriate psychosocial support. Throughout its pages, the guide explores mental health from multiple angles: its definition, legal framework in Morocco, and the prevalence of disorders such as anxiety and depression—particularly exacerbated among migrants due to their living conditions. It also highlights structural challenges within Morocco’s healthcare system and unequal access to care, especially for migrant populations. Written in an accessible and inclusive style, the document offers practical approaches to support these individuals. It emphasizes the importance of active, nonjudgmental listening, tailored emotional support, and referrals to competent professionals. Tools such as mental health first aid models are enriched with recommendations adapted to the cultural and social realities of migrants in Morocco. The guide adopts a humanistic approach, recognizing mental health as essential to integration and well-being. By addressing issues like discrimination, gender disparities, and precarious living conditions, it underscores the urgency of strengthening therapeutic support systems while integrating community-based strategies to foster resilience. Ultimately, this guide goes beyond assessing the current landscape—it opens ambitious pathways: rethinking support practices, promoting preventive initiatives, and developing sustainable, accessible solutions grounded in Moroccan and decolonial perspectives. It aims to contribute meaningfully to practitioners working to improve the living conditions and mental health of migrants in Morocco.